IMPACT OF LIVER FIBROSIS ON RESULTS OF LIVER HYPERTROPHY AFTER LIVER VENOUS DEPRIVATION
Main Article Content
Abstract
Liver venous deprivation (LVD) is recently used to increase future liver remnant volume before major hepatectomy in treating hepatocellular carcinoma (HCC). HCC patients often have underlying liver disease and cirrhosis, which may affect the degree of liver hypertrophy after LVD. This report aims to evaluate the impact of liver fibrosis on the effectiveness of liver hypertrophy after LVD in HCC patients. A retrospective study was conducted on 44 HCC patients who underwent successful hepatectomy after LVD. Based on postoperative histopathological results, these patients were divided into non-fibrosis group F1-2 and fibrosis group F3-4. There was a significant change in FLR volume for all patients before and 3 weeks after LVD (p < 0.001). LVD resulted in a significantly higher rate of liver hypertrophy in the F1-2 fibrosis group than in the F3-4 group (61% vs. 47%, p = 0.016). LVD before major hepatectomy may induce significant FLR hypertrophy and increase the resectability for HCC patients. The F1-2 fibrosis group achieved a statistically significantly higher rate of liver hypertrophy than the F3-4 fibrosis group.
Article Details
Keywords
Portal and hepatic vein embolization, cirrhosis, liver hypertrophy, hepatocellular carcinoma.
References
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