EFFECTIVENESS OF NASAL CONTINUOUS POSITIVE AIRWAY PRESSURE IN THE TREATMENT OF PEDIATRIC ACUTE RESPIRATORY FAILURE AT VIETNAM NATIONAL CHILDREN'S HOSPITAL

Trần Duy Vũ1,, Nguyễn Thị Yến1, Lê Thị Hồng Hanh2
1 Hanoi Medical University
2 Vietnam National Children's Hospital

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Abstract

Objective: To evaluate the effectiveness of Nasal Continuous Positive Airway Pressure (NCPAP) via Benveniste valve in the treatment of pediatric acute respiratory failure at the Respiratory Center of Vietnam National Children's Hospital. Subjects and methods: This prospective descriptive study included 31 patients treated for acute respiratory failure by NCPAP at the Respiratory Center of Vietnam Natinonal Children's Hospital from 7/2020 to 6/2021. Results: The success rate of NCPAP was 61.3%, the mean time was 5.23 days. After 6 hours, the arterial blood gas was significantly improved: PaO2 increased from 77.98 mmHg to 110.33 mmHg, SaO2 increased from 87.67% to 95.95%, PaCO2 decreased from 59.02 mmHg to 54.48 mmHg, pH increased from 7.32 to 7.37. The rate of children with tachypnea decreased from 96.8% to 45.2%, the rate of chest indrawing decreased from 90.3% to 58.1%, the rate of cyanosis fell from 96.8% to 35.5%, and the rate of irritability or lethargy dropped from 96.8% to 22.6%. Conclusion: Nasal Continuous Positive Airway Pressure via Benveniste valve is effective in improving arterial blood gas as well as clinical signs of pediatric acute respiratory failure at the time after 6 hours.

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References

1. Friedman ML, Nitu ME. Acute Respiratory Failure in Children. Pediatr Ann. 2018;47(7):e268-e273. doi:10.3928/19382359-20180625-01
2. Machen HE, Mwanza ZV, Brown JK, et al. Outcomes of Patients with Respiratory Distress Treated with Bubble CPAP on a Pediatric Ward in Malawi. J Trop Pediatr. 2015;61(6):421-427. doi:10.1093/tropej/fmv052
3. Trần Văn Trung (2009), Đánh giá hiệu quả của thở áp lực dương liên tục qua mũi trong điều trị suy hô hấp do viêm phổi ở trẻ dưới 5 tuổi tại bệnh viện Xanh Pôn, Trường Đại học Y Hà Nội.
4. Thia LP, McKenzie SA, Blyth TP, Minasian CC, Kozlowska WJ, Carr SB. Randomised controlled trial of nasal continuous positive airways pressure (CPAP) in bronchiolitis. Arch Dis Child. 2008;93(1):45-47. doi:10.1136/adc.2005.091231
5. Kinikar A, Kulkarni R, Valvi C, Gupte N. Use of indigenous bubble CPAP during swine flu pandemic in Pune, India. Indian J Pediatr. 2011;78(10):1216-1220. doi:10.1007/s12098-011-0389-x
6. Jayashree M, KiranBabu H, Singhi S, Nallasamy K. Use of Nasal Bubble CPAP in Children with Hypoxemic Clinical Pneumonia—Report from a Resource Limited Set-Up. J Trop Pediatr. 2016;62(1):69-74. doi:10.1093/ tropej/fmv063