TÌNH TRẠNG KHÁNG KHÁNG SINH CỦA KLEBSILLA PNEUMONIAE GÂY NHIỄM KHUẨN HUYẾT Ở CÁC BỆNH NHÂN MỚI NHẬP VIỆN ĐIỀU TRỊ TẠI BỆNH VIỆN HỮU NGHỊ ĐA KHOA NGHỆ AN

Abstract

Objectives: Evaluating the antibiotic resistanCe of Klebsiella pneumoniae bacteria causing bacteremia in newly hospitalized patients at Nghe An General Friendship Hospital. Subjects and methods: Cross-sectional descriptive study on 246 new infectious patients treated at Nghe An General Friendship Hospital with positive blood culture results at the time of admission from September 2021 to September 2023. Results: The rate of septicemia due to Klebsiella pneumoniae accounts for 17.1%. By source of infection: Respiratory 19.4%; digestion 22.5%; urinary tract 6.1%; soft tissue 8.3%; biliary tract 20%; blood 25%. Antibiotic resistanCe of Klebsiella pneumonia bacteria: meropenem resistanCe 19%; Piperacillin 21.4%; Cotrimoxazole 40%; doxycycline 39%; levofloxacin 25%; ciprofloxacin 28.6%; Cefepime 30%. The MDR rate of Klebsiella pneumoniae is 40.2% and the ESBL (+) production rate of Klebsiella pneumoniae is 19%. Conclusion: Antibiotic resistanCe in patients with septiCemia caused by Klebsiella pneumoniae when first hospitalized for treatment at Nghe An General Friendship Hospital is on the rise.