THE CAUSES OF SEPSIS IN PRETERM NEWBORNS AT HANOI OBSTETRICS AND GYNECOLOGY HOSPITAL AND SOME RELATED FACTORS

Trọng Hưng Mai, Lương Nhân Trần, Thị Quỳnh Nga Nguyễn, Tuấn Anh Trần, Tuấn Anh Trần, Thị Luyến Hoàng, Thu Hương Nguyễn

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Abstract

Objective: This study aimed to determine the causes of sepsis in preterm newborns at Hanoi Obstetrics and Gynecology Hospital and some related factors. Subject and method: A descriptive study of 106 preterm newborns diagnosed with neonatal sepsis and had positive blood culture results at Hanoi Obstetrics and Gynecology Hospital from August 2022 to May 2024. Results: The main cause of sepsis in preterm newborns was Gram – negative bacteria accounting for 78.9%, Gram – positive bacteria accounted for 15.6%, fungi accounted for 5.5%. In early onset neonatal sepsis, Gram – negative bacteria accounted for the highest proportion, the most common was E. coli (44%). In late onset neonatal sepsis, Gram – negative bacteria also accounted for the highest proportion, the most common were K. pneumoniae (36.9%) and E. coli (32.1%). Some factors associated with early onset neonatal sepsis included maternal fever in labor, vaginitis, prolonged rupture of membranes more than 18 hours, dirty amniotic fluid. Some factors associated with late onset neonatal sepsis included gestational age less than 32 weeks, birth weight less than 1500g, insertion of central venous catheter. Conclusion: The main cause of sepsis in preterm newborns was Gram – negative bacteria, the most common were E. coli and K. pneumoniae. Some factors associated with early onset neonatal sepsis included maternal fever in labor, vaginitis, prolonged rupture of membranes more than 18 hours, dirty amniotic fluid. Some factors associated with late onset neonatal sepsis included gestational age less than 32 weeks, birth weight less than 1500g, insertion of central venous catheter.

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References

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