NGHIÊN CỨU NỒNG ĐỘ NON-HDL-CHOLESTEROL VÀ MỘT SỐ YẾU TỐ LIÊN QUAN Ở BỆNH NHÂN ĐÁI THÁO ĐƯỜNG TYPE 2 TẠI BỆNH VIỆN TRƯỜNG ĐẠI HỌC Y DƯỢC CẦN THƠ

Abstract

Background: The non-HDL-C index has a higher diagnostic value and greater integrity compared to the LDL-C index in diagnosing lipid disorders and predicting cardiovascular complications. Besides cardiovascular complications, lipid disorders are also closely associated with other conditions such as diabetes mellitus (DM), one of the most severe chronic diseases globally. Objectives: (i) To investigate the non-HDL-C levels in patients with type 2 diabetes mellitus at Can Tho University of Medicine and Pharmacy Hospital; (ii) To examine some factors related to plasma non-HDL-C levels in patients with type 2 diabetes mellitus at Can Tho University of Medicine and Pharmacy Hospital. Methods: A cross-sectional descriptive study was conducted on 236 patients with type 2 diabetes mellitus at Can Tho University of Medicine and Pharmacy Hospital. Results: The levels and rates of abnormalities in blood lipid parameters: TC, TG, LDL-C, HDL-C, and non-HDL-C were 5.25 ± 1.53 (48.3%), 2.81 ± 2.29 (68.6%), 2.94 ± 1.28 (38.1%), 1.19 ± 0.42 (39%), and 4.06 ± 1.46 (44.5%). Among overweight-obese patients, non-smokers, and those with elevated LDL-C, the rate of increased non-HDL-C was higher compared to non-overweight-obese patients, smoking habit, and those with optimal LDL-C levels, with a statistically significant difference (p<0.05). Conclusion: The non-HDL-C level in patients with type 2 diabetes mellitus was 4.06 ± 1.46 (44.5%). Factors associated with increased non-HDL-C levels included overweight-obesity, elevated LDL-C, and smoking. However, there was an inverse correlation observed between non-smokers and increased non-HDL-C levels