CLINCAL CASE REPORT: EARLY RESULTS OF FLUORESCENCE LYMPH NODE MAPPING USING INDOCYANINE GREEN FOR LAPAROSCOPIC RIGHT HEMICOLECTOMY
Main Article Content
Abstract
Background: With the development of surgical technology, indocyanine green (ICG) fluorescence navigation systems may be useful in various areas of colorectal surgery, including tumor location confirmation, bowel perfusion, ureter identification, and lymph node mapping. This review provides an overview of the current status of ICG-based navigation surgery in right colon, emphasizing its role in lymphatic flow mapping. Case report: Viet Duc University Hospital for the first time deployed ICG application in a 46-year-old male patient diagnosed with right colon cancer with the goal of evaluating lymphatic pathways. The results of ICG-guided right colon lymphadenectomy successfully and safely performed, Lymphatic mapping has changed the scope of surgery, beyond the scope of standard D3 lymphadenectomy. Conclusions: Fluorescence lymph node mapping (FLNM) could be considered a promising new strategy to potentially increase harvested D3 lymph node counts in colon cancer surgery. The use of FLNM has the potential to change the paradigm of oncological surgery, but the clinical benefits and oncological advantages are not yet clear. Therefore, cautious application and further research are needed.
Article Details
Keywords
ICG (Indocyanine green); lymphatic mapping; ICG-guided lymphadenectomy; colorectal cancer.
References
2. Figueredo A, Coombes ME, Mukherjee S. Adjuvant therapy for completely resected stage II colon cancer. Cochrane Database Syst Rev 2008;2008(3):CD005390.
3. Park, S.Y.; Park, J.S.; Kim, H.Y.; Woo, I.T.; Park, I.K.; Choi, G.-S. Indocyanine green fluorescence imaging-guided laparoscopic surgery could achieve radical d3 dissection in patients with advanced right-sided Colon Cancer. Dis. Colon. Rectum. 2020, 63, 441–449.
4. Petz, W.; Bertani, E.; Borin, S.; Fiori, G.; Ribero, D.; Spinoglio, G. Fluorescence-guided D3 lymphadenectomy in robotic right colectomy with complete mesocolic excision. Int. J. Med. Robot 2020, 28, e2217.
5. Hohenberger W, Weber K, Matzel K, Papadopoulos T, Merkel S. Standardized surgery for colonic cancer: complete mesocolic excision and central ligation–technical notes and outcome. Colorectal disease. 2009;11(4):354-364.
6. Chen SL, Bilchik AJ. More extensive nodal dissection improves survival for stages I to III of colon cancer: a population-based study. Ann Surg 2006;244:602-10.
7. Jamieson JK, Dobson JF. The lymphatics of the colon. Proc R Soc Med 1909;2:149-74.
8 . Dip F, Boni L, Bouvet M, et al. Consensus Conference Statement on the General Use of Near-Infrared Fluorescence Imaging and Indocyanine Green Guided Surgery: Results of a Modified Delphi Study. Ann Surg 2020; Epub ahead of print.
9. Tajima Y, Yamazaki K, Masuda Y, et al. Sentinel node mapping guided by indocyanine green fluorescence imaging in gastric cancer. Ann Surg 2009;249:58-62.
10. Le Voyer TE, Sigurdson ER, Hanlon AL, et al. Colon cancer survival is associated with increasing number of lymph nodes analyzed: a secondary survey of intergroup trial INT-0089. J Clin Oncol 2003;21:2912-9.