KẾT QUẢ BƯỚC ĐẦU SỬ DỤNG KHÁNG SINH DỰ PHÒNG TẠI KHOA NGOẠI TỔNG HỢP – BỆNH VIỆN ĐA KHOA TỈNH YÊN BÁI

Abstract

Background: This study aims to evaluate the effectiveness of prophylactic antibiotic use in clean surgeries at the General Surgery Department of Yen Bai Provincial General Hospital. Subjects and Methods: A retrospective and prospective cross-sectional descriptive study was conducted on 191 patients who underwent laparoscopic cholecystectomy (LC) and laparoscopic inguinal hernia repair (LIHR) during two phases: Phase 1 from August 2022 to June 2023 (85 patients) and Phase 2 from August 2023 to June 2024 (106 patients) after the implementation of prophylactic antibiotic. Results: The differences in age, gender, and ASA scores between the two Phases were not statistically significant (p>0.05). In Phase 1, 100% of patients used antibiotics for extended post-surgery. Among those who underwent LC, 62.5% used antibiotics for 4-6 days, and 97.9% used combined antibiotics. For LIHR, 100% of cases used antibiotics for more than 4 days. In Phase 2, the use of prophylactic antibiotics, specifically Cephalosporin II, accounted for 87.1% and 84% in the two types of surgeries, respectively. The rate of antibiotic administration within 60 minutes before surgery reached 91.9% in LC and 95.5% in LIHR. No cases of extended antibiotic use beyond 24 hours post-surgery were observed. The length of hospital stay after LC decreased from 5.7 ± 1.7 to 4 ± 1.4 days, with an average cost reduction of 1,086,000 VND. For LIHR, the length of stay decreased from 6.2 ± 1.4 to 2.9 ± 1.0 days, with an average cost reduction of 1,891,000 VND (p<0.05). Conclusion: The use of prophylactic antibiotics in surgery is a safe and effective treatment method, helping to reduce hospital stay and treatment costs.