SEXUAL DYSFUNCTION IN DEPRESSED FEMALES RECEIVING SELECTIVE SEROTONIN REUPTAKE INHIBITORS

Nguyễn Phương Linh1,, Nguyễn Văn Tuấn2
1 National Mental Health Institute, Bach Mai Hospital
2 Hanoi Medical University

Main Article Content

Abstract

Background:  Sexual dysfunction is a common problem in depressed female patients receiving selective serotonin reuptake inhibitors (SSRIs). However, in Vietnam, there have been no studies on this issue, although it seriously affects treatment adherence as well as quality of life and the cost of medical services later. Research objectives: To evaluate side-effect on sexual dysfunction in female patients with depression treated with SSRIs at the National Institute of Mental Health. Subjects and methods: A cross-sectional descriptive study at 3 times of 58 depressed female patients treated with SSRIs at the National Institute of Mental Health from September 2020 to July 2021, using the Female Sexual Function Index (FSFI). Results: the general age of the group with sexual dysfunction was 39.23 ± 12.69 years. Pain during vaginal penetration accounted for the highest percentage with 89.66% and the lowest was vaginal lubrication with 67.24%. The mean FSFI score decreased from 20.42±5.95 to 13.56±4.34 demonstrating a statistically significant decline with p <0.01 at both time points after 2 weeks and after 4 weeks of treatment. Conclusion: The most common sexual dysfunction in depressed female patients treated with SSRIs was pain during vaginal penetration. The decline was statistically significant with p<0.01 after 4 weeks of treatment.

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References

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