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Date Published: 02/12/2024
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DOI: https://doi.org/10.51298/vmj.v544i3.12041
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Vol. 544 No. 3 (2024)
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Nguyễn, T. Đức, & Nguyễn, T. C. (2024). COMPARISON OF THE EFFICACY OF SHIVERING PROPHYLAXIS BETWEEN INTRAVENOUS KETAMINE 0.2 MG/KG AND ONDANSETRON 4 MG AFTER SPINAL ANESTHESIA FOR CESAREAN SECTION. Vietnam Medical Journal, 544(3). https://doi.org/10.51298/vmj.v544i3.12041

COMPARISON OF THE EFFICACY OF SHIVERING PROPHYLAXIS BETWEEN INTRAVENOUS KETAMINE 0.2 MG/KG AND ONDANSETRON 4 MG AFTER SPINAL ANESTHESIA FOR CESAREAN SECTION

Tiến Đức Nguyễn, Thanh Chương Nguyễn

Main Article Content

Abstract

Objective: Comparison of the efficacy of shivering prophylaxis between intravenous ketamine 0.2 mg/kg and ondansetron 4 mg after spinal anesthesia for cesarean section. Subjects and methods: A prospective, randomized clinical trial was conducted comparing two groups: 50 patients who received intravenous ketamine 0.2 mg/kg (group K) and 50 patients who received intravenous ondansetron 4 mg (group O), at Military Hospital 354, from December 2022 to June 2023. Results: The rate of intraoperative shivering in group O was 34%, while in group K it was 14%, a statistically significant difference. The rate of postoperative shivering in group O was 8%, while in group K it was 2%. The duration of intraoperative shivering in group O was 12.8 ± 3.5 minutes, compared to 14.1 ± 4.6 minutes in group K. The duration of postoperative shivering in group O was 12.5 ± 2.9 minutes, while it was 10 minutes in group K. The severity of intraoperative shivering in group O was 23.5% at grade 2 and 76.5% at grade 3, while in group K it was 42.9% at grade 2 and 57.1% at grade 3. Postoperative shivering severity in group O was 100% at grade 2, while in group K it was 100% at grade 1. All patients who experienced shivering did so within the first 20 minutes after spinal anesthesia, primarily within the first 10 minutes. Conclusion: Ketamine and ondansetron are effective in preventing shivering after spinal anesthesia for cesarean section.

Article Details

Keywords

shivering prophylaxis, ketamine, ondansetron, spinal anesthesia.

References

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