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Date Published: 02/12/2024
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DOI: https://doi.org/10.51298/vmj.v544i3.12050
Issue
Vol. 544 No. 3 (2024)
Section
Các bài báo
How to Cite
Nguyễn, T. M., Hoàng, T. V., & Cấn, V. M. (2024). CORRELATION BETWEEN PLASMA NESFATIN-1 CONCENTRATIONS AND CLINICAL INDICATORS IN A GROUP OF PATIENTS WITH DIABETES (NEWLY DETECTED, UNTREATED AND TREATED) AT THE 19-8 HOSPITAL. Vietnam Medical Journal, 544(3). https://doi.org/10.51298/vmj.v544i3.12050

CORRELATION BETWEEN PLASMA NESFATIN-1 CONCENTRATIONS AND CLINICAL INDICATORS IN A GROUP OF PATIENTS WITH DIABETES (NEWLY DETECTED, UNTREATED AND TREATED) AT THE 19-8 HOSPITAL

Thị Minh Nguyễn, Trung Vinh Hoàng, Văn Mão Cấn

Main Article Content

Abstract

Objective: Determine the concentration of Nesfatin-1 in serum and the relationship between Nesfatin-1 concentration and some clinical parameters in a group of patients with type 2 diabetes. Subjects and Methods of Research: The study was conducted on 60 patients with type 2 diabetes, divided into 2 groups: newly detected, untreated type 2 diabetes, and type 2 diabetes treated at the 19-8 Hospital. The methods used in the study included measuring the concentration of Nesfatin-1 using BioVendor, and conducting some clinical tests including BMI, WHR, age, and paraclinical tests (including HbA1c and blood glucose). Results: The concentration of Nesfatin-1 and blood glucose levels showed a statistically significant difference (p < 0.05) between the two groups of type 2 diabetes studied. In addition, the Nesfatin-1 index, along with the indices of age, BMI, WHR (waist-hip ratio), and HbA1c in the two study groups, did not show any statistically significant difference (p > 0.05). The study results also showed a positive correlation between blood glucose index and HbA1c and WHR (waist-hip ratio) in the T2DM groups (r = 0.68-0.75; p = 0.001 and r = 0.439; p = 0.015). Conclusion: Nesfatin-1 concentration and blood glucose levels were statistically significantly different between the two study groups. Nesfatin-1 concentration was positively correlated with clinical and paraclinical parameters with a significant difference.

Article Details

Keywords

Type 2 diabetes; Nesfatin-1; HbA1c; newly diagnosed; treated.

References

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