CLINICAL FEATURES CLINICAL FEATURES , MAGNETIC RESONANCE IMAGING AND INITIAL EVALUATION OF THE EFFECTIVENESS OF RIVAROXABAN IN THE TREATMENT OF CEREBRAL VENOUS THROMBOSIS

Phạm Thị Ngọc Linh1,, Võ Hồng Khôi2, Nguyễn Ngọc Hòa3
1 Hanoi Medical University
2 Bach Mai Hospital
3 Nghe An Friendship General Hospital

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Abstract

Objective:To describe clinical features, magnetic resonance imaging and initial evaluate the effectiveness of rivaroxaban in the treatment of cerebral venous thrombosis. Subjects and methods: A prospective, descriptive study of 38 patients with cerebral venous thrombosistreated at the Department of Neurology, Bach Mai Hospital from March 2020 to June 2021. Results: Mean age was 42.4 ± 14.8, male/female ratio was 1.2:1. Acute onset was seen in 6 patients (15.8%), subacute in 31 (81.6%) and chronic in 1 (2.6%). Most cases onset frequently with headache (94.7%), followed by hemiparesis (34.2%) and seizure (28.9%). 25 patients (65.8%) had parenchymal brain lesions in MRI, including venous infarct (31.6%), hemorrhage (21.1%), hemorrhagic infarct (18.4%). Involvement of the superior sagittal sinus was found in 73.7% patients, the transverse sinus in 63.2% patients and sigma sinus 47.4% patients. The initial evaluation of the effectiveness of rivaroxaban in the treatment of cerebral venous thrombosis is quite promising. 94.7% of patients had good recovery with mRS score from 0-1 point. The recurrence rate was low, with 2.6% of venous thromboembolic events recurred.

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References

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