Article Sidebar

PDF
Date Published: 18/10/2021
Abstract Views: 201
Views PDF: 159
DOI: https://doi.org/10.51298/vmj.v506i1.1206
Issue
Vol. 506 No. 1 (2021)
Section
Các bài báo
How to Cite
Thị Ngọc Linh, P. ., Hồng Khôi, V. ., & Ngọc Hòa, N. (2021). CLINICAL FEATURES CLINICAL FEATURES , MAGNETIC RESONANCE IMAGING AND INITIAL EVALUATION OF THE EFFECTIVENESS OF RIVAROXABAN IN THE TREATMENT OF CEREBRAL VENOUS THROMBOSIS. Vietnam Medical Journal, 506(1). https://doi.org/10.51298/vmj.v506i1.1206

CLINICAL FEATURES CLINICAL FEATURES , MAGNETIC RESONANCE IMAGING AND INITIAL EVALUATION OF THE EFFECTIVENESS OF RIVAROXABAN IN THE TREATMENT OF CEREBRAL VENOUS THROMBOSIS

Phạm Thị Ngọc Linh1,, Võ Hồng Khôi2, Nguyễn Ngọc Hòa3
1 Hanoi Medical University
2 Bach Mai Hospital
3 Nghe An Friendship General Hospital

Main Article Content

Abstract

Objective:To describe clinical features, magnetic resonance imaging and initial evaluate the effectiveness of rivaroxaban in the treatment of cerebral venous thrombosis. Subjects and methods: A prospective, descriptive study of 38 patients with cerebral venous thrombosistreated at the Department of Neurology, Bach Mai Hospital from March 2020 to June 2021. Results: Mean age was 42.4 ± 14.8, male/female ratio was 1.2:1. Acute onset was seen in 6 patients (15.8%), subacute in 31 (81.6%) and chronic in 1 (2.6%). Most cases onset frequently with headache (94.7%), followed by hemiparesis (34.2%) and seizure (28.9%). 25 patients (65.8%) had parenchymal brain lesions in MRI, including venous infarct (31.6%), hemorrhage (21.1%), hemorrhagic infarct (18.4%). Involvement of the superior sagittal sinus was found in 73.7% patients, the transverse sinus in 63.2% patients and sigma sinus 47.4% patients. The initial evaluation of the effectiveness of rivaroxaban in the treatment of cerebral venous thrombosis is quite promising. 94.7% of patients had good recovery with mRS score from 0-1 point. The recurrence rate was low, with 2.6% of venous thromboembolic events recurred.

Article Details

Keywords

Cerebral venous thrombosis, rivaroxaban

References

1. Gustavo Saposnik, Fernando Barinagarrementeria, Robert D Brown Jr, et al. (2011). Diagnosis and management of cerebral venous thrombosis: a statement for healthcare professionals from the American Heart Association/American Stroke Association. Stroke, 42 (4), 1158-1192.
2. Jonathan M Coutinho, José M Ferro, Patrícia Canhao, et al. (2009). Cerebral venous and sinus thrombosis in women. Stroke, 40 (7), 2356-2361.
3. Lê Văn Thính, Trịnh Tiến Lực (2010). Nhận xét một số đặc điểm lâm sàng, cận lâm sàng và điều trị huyết khối tĩnh mạch não. Tập san Hội Thần kinh học Việt Nam, 2, 10.
4. Trịnh Tiến Lực (2020). Nghiên cứu đặc điểm lâm sàng và hình ảnh học của bệnh nhân huyết khối tĩnh mạch não Luận án Tiến sỹ y học, Đại học Y Hà Nội.
5. Lê Văn Minh. (2014), Nghiên cứu đặc điểm lâm sàng, hình ảnh não, một số yếu tố nguy cơ và giá trị của D-Dimer trong chẩn đoán huyết khối tính mạch não, Luận án Tiến sỹ Y học, Học viện Quân Y.
6. José M Ferro, Jonathan M Coutinho, Francesco Dentali, et al. (2019). Safety and efficacy of dabigatran etexilate vs dose-adjusted warfarin in patients with cerebral venous thrombosis: a randomized clinical trial. JAMA neurology, 76 (12), 1457-1465.