ĐẶC ĐIỂM HỘI CHỨNG CHUYỂN HÓA Ở PHỤ NỮ LOÃNG XƯƠNG NGUYÊN PHÁT

Abstract

Object: Metabolic syndrome and osteoporosis are two common conditions that receive little attention in postmenopausal women. These conditions are often only detected when serious complications, such as cardiovascular events and fractures, have occurred. Objective: To determine the prevalence of metabolic syndrome and assess some related factors in women with primary osteoporosis. Subjects and Methods: A descriptive, cross-sectional study was conducted on 99 postmenopausal female patients diagnosed with primary osteoporosis who visited or were treated at Bach Mai Hospital and Hanoi Medical University Hospital from August 2023 to August 2024. Results: The prevalence of metabolic syndrome in postmenopausal women with primary osteoporosis is 52.5%, with elevated glucose being the most common (57.6%). Overweight, obese, or physically inactive individuals have a higher risk of developing metabolic syndrome, 4.8 and 3.9 times higher, respectively (OR = 4.8; 3.9). No association was found between total calcium levels, vitamin D3, T-score at the femoral neck, and lumbar spine between the groups with and without metabolic syndrome (p > 0.05). However, there is a positive correlation between increased waist circumference and T-score at the femoral neck and lumbar spine (p < 0.05). Conclusion: The prevalence of metabolic syndrome in women diagnosed with primary osteoporosis is quite high, with elevated glucose being the most common factor. Overweight, obesity, or physical inactivity increase the risk of metabolic syndrome. Increased waist circumference is associated with higher bone density. Identifying and understanding the relationship between metabolic syndrome and osteoporosis is crucial for developing effective prevention and treatment strategies.