NỒNG ĐỘ VITAMIN D HUYẾT THANH TRÊN BỆNH NHÂN VIÊM NHA CHU VÀ NGƯỜI CÓ MÔ NHA CHU LÀNH MẠNH

Abstract

Objective: This current study was performed to compare and evaluate serum vitamin D levels between the periodontitis group and the periodontally healthy group. Method: Sixty patients (29 in the periodontitis group (PG) and 31 in the periodontally healthy group (HG), diagnosed according to American Academy of Periodontology, AAP 2015) were included in the study at the Department of Odonto-Stomatology, University of Medicine and Pharmacy at Ho Chi Minh City (UMP) from October 2022 to August 2023. Periodontal examination assessed and recorded periodontal indicators related to the diagnosis of periodontitis according to AAP 2015, including: plaque index (PLI); gingival index (GI); probing periodontal pocket depth (PPD); clinical attachment loss (CAL); bleeding on probing (BOP); assessment of bone loss on X-ray. Study participants were then transferred to the testing center to collect 3 mL of blood for serum vitamin D concentration testing. Serum vitamin D concentration was then analyzed using the Cobas 6000 module601 (electro-chemiluminescence immunoassay) testing technique of the testing center according to the manufacturer's procedure. Results: The mean serum vitamin D concentration of the study sample was 22.4 ± 7.1 (ng/mL). Of these, 34 (56.67%) people had adequate serum vitamin D and 26 (43.33%) people had serum vitamin D deficiency. Regarding serum vitamin D status, 26 (43.33%) people had serum vitamin D deficiency, 26 (43.33%) people had serum vitamin D deficiency and 8 (13.34%) people had normal serum vitamin D. The mean serum vitamin D concentration in the periodontitis group was 20.42 ± 6.5 (ng/mL)1, whereas in the healthy group, it was 24.26 ± 7.24 (ng/mL), and this difference exhibited statistical significance (p = 0.035). Conclusion: There was a statistically significant difference in mean serum vitamin D concentrations between the periodontitis patients and the healthy periodontal group.