COGNITIVE IMPAIRMENT CHARACTERISTICS IN PARKINSON'S DISEASE PATIENTS

Phước Đông Hà, Thanh Bình Nguyễn

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Abstract

Objective: To describe the characteristics of cognitive impairment and analyze some factors related to cognitive impairment in Parkinson's disease patients at the National Geriatric Hospital. Subject and methodology: Cross-sectional study; subjects are patients diagnosed with Parkinson's disease who were examined, treated and assessed cognitive function using a neuropsychological test at the National Geriatric Hospital from January 1st, 2024 to August 31st, 2024. Results: The study enrolled 113 patients. The average age is 69 ± 7,931, female accounted for 64,6%. The proportion of patients with cognitive impairment is 66,3%, with 27.4% experiencing mild cognitive impairment and 38.9% having dementia. Among Parkinson's patients with cognitive impairment, executive function decline is the most common, affecting 96% of patients. There are statistically significant differences in the rates of cognitive impairment across different age groups, educational levels, occupations, Hoehn and Yahr stages, age at onset, duration of Parkinson’s disease and UPDRS (III) scores with p < 0.05. Conclusion: 27.4% of Parkinson's disease patients have mild cognitive impairment and 38.9% have dementia. Executive function impairment is one of the prominent feature of cognitive impairment in these patients. Factors such as age, education level, occupation, Hoehn and Yahr stage, age at onset of Parkinson’s disease, duration of Parkinson’s disease and UPDRS (III) scores are associated with cognitive impairment in Parkinson's disease patients.

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References

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