SO SÁNH CHẤT LƯỢNG HỒI TỈNH VÀ TÁC DỤNG KHÔNG MONG MUỐN CỦA DESFLURANE SO VỚI SEVOFLURANE CHO PHẪU THUẬT CẮT TUYẾN GIÁP QUA NỘI SOI ĐƯỜNG MIỆNG (TOETVA

Abstract

Objective: To compare the quality of emergence and adverse effects of desflurane versus sevoflurane in transoral endoscopic thyroidectomy vestibular approach (TOETVA). Methods: A prospective, randomized controlled clinical trial. Sixty patients were randomly assigned into two groups: Group D (desflurane, n=30) and Group S (sevoflurane, n=30). Results: Group D had significantly faster recovery times compared to Group S, with spontaneous breathing, eye-opening, and extubation times of 3.45 ± 0.95 minutes, 5.70 ± 1.88 minutes, and 7.59 ± 2.12 minutes, respectively, compared to 5.18 ± 0.86 minutes, 8.07 ± 1.00 minutes, and 10.95 ± 2.00 minutes in Group S. These differences were statistically significant (p<0.05). Moreover, the cough reflex upon immediate extubation was better in Group D (90%) than in Group S (75%), with a statistically significant difference (p<0.05). Besides, adverse effects such as nausea, shivering, restlessness, and mild agitation were observed in both groups, with no significant difference (p>0.05). Conclusion: Desflurane and sevoflurane are both safe and effective anesthetic options for transoral endoscopic thyroidectomy vestibular approach (TOETVA). Furthermore, the research could explore that desflurane offers advantages in faster recovery times and earlier restoration of respiratory reflexes compared to sevoflurane.