THE RATIO OF TOTAL CHOLESTEROL, TRIGLYCERIDE TO HDL-CHOLESTEROL IN TYPE 2 DIABETES PATIENTS
Main Article Content
Abstract
Background: Researchers have reported an association between dyslipidemia and the incidence of diabetes mellitus and metabolic syndrome in adults. However, the ratio of total cholesterol (TC)/high-density lipoprotein cholesterol (HDL-c), the ratio of triglycerides (TG)/HDL-c and the relationship between blood lipid indices according to gender subgroups in diabetic patients are limited. Method: This study collected data on the blood lipid index of diabetic patients, aged 18 years and older, undergoing outpatient treatment at Le Van Thinh Hospital in Ho Chi Minh City. Results: No differences were found in the TC/HDL-c, TG/HDL-c, and LDL/HDL-c ratios according to gender. In the group with MetS, both men and women had a higher TC/HDL-c ratio and TG/HDL-c ratio than the other group (p<0.05). The group with HDL-c levels between 40 and 59 mg/dL accounts for the highest proportion in both men and women (p<0.05). Conclusion: TC/HDL-c and TG/HDL-c ratios were high in the study population, and clearly increased in the group with MetS according to gender subgroups, indicating the significance of control blood lipid solutions as well as MetS in diabetic patients.
Article Details
Keywords
total cholesterol, triglyceride, HDL-cholesterol, type 2 diabetes.
References
2. Giles LA. Hyperlipidemia Prevention and Management Utilizing Lifestyle Changes. J Midwifery Womens Health. 2024; 69(3): 361-369.
3. Ling JZJ., Montvida O., Khunti K., et al. Therapeutic inertia in the management of dyslipidaemia and hypertension in incident type 2 diabetes and the resulting risk factor burden: Real-world evidence from primary care. Diabetes Obes. Metab. 2021; 23: 1518–1531.
4. Lelis DF, Calzavara JVS, Santos RD, et al. Reference values for the triglyceride to high-density lipoprotein ratio and its association with cardiometabolic diseases in a mixed adult population: The ELSA-Brasil study. J Clin Lipidol. 2021; 15(5): 699-711.
5. Lelis DF, Calzavara JVS, Santos RD, et al. Reference values for the triglyceride to high-density lipoprotein ratio and its association with cardiometabolic diseases in a mixed adult population: The ELSA-Brasil study. J Clin Lipidol. 2021; 15(5): 699-711.
6. Kosmas CE, Rodriguez Polanco S, Bousvarou MD, Papakonstantinou EJ, Peña Genao E, Guzman E, Kostara CE. The Triglyceride/High-Density Lipoprotein Cholesterol (TG/HDL-C) Ratio as a Risk Marker for Metabolic Syndrome and Cardiovascular Disease. Diagnostics (Basel). 2023; 13(5): 929.
7. Abbasian M, Delvarianzadeh M, Ebrahimi H, Khosravi F. Lipid ratio as a suitable tool to identify individuals with MetS risk: A case- control study. Diabetes Metab Syndr. 2017;11 Suppl 1: S15-S19.
8. Nie G, Hou S, Zhang M, Peng W. High TG/HDL ratio suggests a higher risk of metabolic syndrome among an elderly Chinese population: a cross-sectional study. BMJ Open. 2021; 11(3): e041519.
9. Wang, M., Liu, M., Li, F. et al. Gender heterogeneity in dyslipidemia prevalence, trends with age and associated factors in middle age rural Chinese. Lipids Health Dis 19, 135 (2020). https://doi.org/10.1186/s12944-020-01313-8.
10. Holven KB, Roeters van Lennep J. Sex differences in lipids: A life course approach. Atherosclerosis. 2023; 384: 117270.