LÂM SÀNG VÀ BIẾN CHỨNG KHI NHẬP VIỆN CỦA BỆNH NHÂN SỎI ĐƯỜNG MẬT THEO NHÓM TUỔI

Abstract

Objective: To analyze and compare gallstone disease's clinical features and complications between age groups. Subjects and Methods: A cross-sectional study was conducted on 1163 patients with gallstone disease, with 1383 inpatient treatments at the 108 Military Central Hospital in 2021-2022. The study population was divided into three groups: Group <60 years old (n=547), group 60 to 79 years old (n=630), and group ≥ 80 years old (n=206); comparing clinical symptom indicators, infection status, bile duct obstruction, and complications of the disease at the time of admission. Results: In the study population, there was no difference in gender ratio, right lower quadrant pain, jaundice, and Charcot's triad (P>0.05). Additionally, the infection status increased with age (fever, increased white blood cells, and increased neutrophils increased with age, P<0.05). Moreover, the rate of hypotension and mental disturbance was significantly higher in elderly patients than in young patients: Hypotension: 9.25%, 8.1%, and 4.6% with P=0.02; Mental disturbance: 4.4%, 1.7%, and 0.4% with P=0.0004; corresponding to 3 decreasing age groups. Finally, the incidence of severe complications of the disease such as sepsis, septicemia, and severe cholangitis all increased with increasing age (P<0.05), especially, patients ≥ 80 years old had a risk of these severe complications twice that of patients <60 years old (P<0.05). Conclusion: Advanced age is a poor prognostic factor for patients with gallstone disease due to the higher frequency of severe complications, especially in patients over 80 years of age. These patients must be treated aggressively and monitored more closely to reduce the risk of death.