CHARACTERISTICS OF OCULAR INVOLVEMENT IN ANKYLOSING SPONDYLITIS PATIENTS
Main Article Content
Abstract
Ojective: To decribe the characteristics of ocular involvements in patients with ankylosing spondylitis. Subjects: 32 patients with ankylosing spondylitis were diagnosed using Modified New York Criteria 1984, in the department of Rheumatology, Bach Mai hospital from December 2020 to April 2021. Methods: Retrospective and cross-sectional descriptive study. Results: The proportion of patients with functional eye symptoms was 18,7 %, with blurred vision symptoms accounted for 15,6 %, red eyes accounted for 3.1 %, and no functional symptoms accounted for 81,3 %. The proportion of patients who had physical manifestatons in the eye was 25 %, of which, uveitis was 21.9 %, conjunctivitis was 3.1%. 75 % of patients did not have physical lesions in the eye. Conclusion: Because of the few symptoms that occur, eye examination is required in patients with ankylosing spondylitis. Although uveitis is uncommon, it can cause irreversible vision loss if not detected and treated promptly.
Article Details
Keywords
ankylosing spondylitis, ocular involvement, uveitis
References
2. Qian Q, Xu X, He H, et al. Clinical patterns and characteristics of ankylosing spondylitis in China. Clin Rheumatol. 2017;36(7):1561-1568. doi:10.1007/s10067-017-3660-3
3. Murray PI, Rauz S. The eye and inflammatory rheumatic diseases: The eye and rheumatoid arthritis, ankylosing spondylitis, psoriatic arthritis. Best Pract Res Clin Rheumatol. 2016;30(5):802-825. doi:10.1016/j. berh. 2016.10.007
4. Monnet D, Breban M, Hudry C, Dougados M, Brézin AP. Ophthalmic findings and frequency of extraocular manifestations in patients with HLA-B27 uveitis: A study of 175 cases. Ophthalmology. 2004;111(4):802-809. doi:10.1016/j. ophtha. 2003.07.011
5. Khan MA, Haroon M, Rosenbaum JT. Acute anterior uveitis and spondyloarthritis: more than meets the eye. Curr Rheumatol Rep. 2015; 17:536.
6. Rosenbaum JT, Asquith M. The microbiome and HLA-B27-associated acute anterior uveitis. Nat Rev Rheumatol. 2018;14(12):704-713. doi:10.1038/s41584-018-0097-2
7. Laura J. Kopplin, George Mount & Eric B. Suhler (2016) Review for Disease of the Year: Epidemiology of HLA-B27 Associated Ocular Disorders, Ocular Immunology and Inflammation, 24:4, 470-475. doi:10.1080/ 09273948.2016.1175642
8. Lie E, Lindström U, Zverkova-Sandström T, et al. Tumour necrosis factor inhibitor treatment and occurrence of anterior uveitis in ankylosing spondylitis: results from the Swedish biologics register. Ann Rheum Dis. 2017;76(9):1515-1521. doi:10.1136/annrheumdis-2016-210931