KẾT QUẢ ĐO ÁP LỰC VÀ NHU ĐỘNG THỰC QUẢN ĐỘ PHÂN GIẢI CAO, ĐO PH TRỞ KHÁNG 24 GIỜ VÀ PEPTEST Ở BỆNH NHÂN CÓ TRIỆU CHỨNG TRÀO NGƯỢC TẠI VÀ NGOÀI THỰC QUẢN

Abstract

Aim: To compare the characteristics of high-resolution manometry (HRM), 24-hour pH -impedance monitoring (pH-I) and Peptest between patients with esophageal symptoms, extraesophageal symptoms and those having both. Methods: We conducted a cross-sectional study among patients having reflux symptoms and indicated with above-mentioned techniques. Patients were then classified into 3 groups: “esophageal symptoms”, “extraesophageal symptoms” and “combined symptoms” groups. Results: 136 patients were eligible, in which 27 patients had esophageal symptoms, 19 patients had extraesophageal symptoms and 90 patients had combined esophageal and extraesophageal symptoms. GerdQ and FSSG scores were significantly lower in patients only having extraesophageal symptoms. There were no significant differences in the prevalence of reflux esophagitis on endoscopy, esophageal sphincter pressures and motility disorders within groups. Acid exposure time (AET), total and acid – weakly acid – non acid reflux events, number of refluxes coming up to the upper third of esophagus also had no significances within groups. There was no difference in the quantatative and qualitative results of Peptest within groups. Conclusion: The characteristics on HRM, pH-I, and Peptest were not significantly different between patients with esophageal symptoms, extraesophageal symptoms and those having both.