CLINICAL AND SUBCLINICAL CHARACTERISTICS OF ACHALASIA PATIENTS AT NGHE AN FRIENDSHIP GENERAL HOSPITAL

Văn Thủy Nguyễn, Văn Hương Nguyễn, Văn Duyệt Phạm

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Abstract

Objective: To describe the clinical and subclinical characteristics of patients with esophageal achalasia at Nghe An Friendship General Hospital. Subjects and Methods: A prospective descriptive study was performed on 39 patients diagnosed with achalasia and underwent laparoscopic Heller myotomy and Dor fundoplication from September 2020 to August 2024. Results: The mean age was 49.03 ± 16.65 years, 12 male patients (30.8%) and 27 female patients (69.2%), male/female ratio was 0.44. The majority of hospitalizations were due to dysphagia (66.7%) and vomiting (17.9%). The average body mass index (BMI) was 19.29 ± 2.61 kg/m², ASA-I accounted for 84.6%, 23.1% had a history of preoperative intervention. Common clinical symptoms were dysphagia (100%), vomiting/regurgitation (100%), chest pain (82.1%), and weight loss (89.7%). Stage classification according to the Eckardt Score in stages I, II and III had rates of (2.6%), (25.6%), and (71.8%), respectively. The X-ray classification of esophageal dilatation was mainly at grade I (33.3%) and II (43.6%). The shape of the esophagus was sigmoid in 20.5% of cases and straight in 79.5%. Endoscopy showed dilatation of the esophagus in 79.5% of patients, fluid and food retention in 71.8%. The average transverse diameter on computed tomography (CT) scans was 4.23 ± 1.78 cm, and 87.2% showed lower esophageal sphincter (LES) narrowing on thoracic CT scans. Conclusion: The clinical symptoms in patients with achalasia in the study were mainly dysphagia, vomiting/regurgitation, chest pain and weight loss with the rates of 100%, 100%, 82.1% and 89.7%, respectively. The rate of straight-shaped esophagus on X-ray accounted for 79.5%. Endoscopy showed esophageal dilatation in 79.5% of patients.

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References

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