ĐẶC ĐIỂM LÂM SÀNG, TRẮC NGHIỆM THẦN KINH TÂM LÝ VÀ HÌNH ẢNH CỘNG HƯỞNG NÃO Ở NGƯỜI BỆNH CAO TUỔI NHỒI MÁU NÃO CÓ SUY GIẢM NHẬN THỨC NHẸ

Abstract

Background: Stroke (the majority is ischemia) is one of diseases having highest mortality rate in the world and leaves many severe sequelae for patients, especially cognitive impairment and dementia. Post-cerebral infarction cognitive impairment not only increase the rate of disability, severely affect the quality of life but also create a burden for families and society. Objective: Describe the clinical characteristics, some neuropsychological tests and brain magnetic resonance imaging of elderly patients with post-cerebral infarction mild cognitive impairment (MCI) at the National Geriatric Hospital (NGH). Subjects and methods: A descriptive case series study was conducted on 50 post-cerebral infarction MCI in or out patients  at the NGH from 8/2023 to 7/2024. Results: The study population had an average age of 71.28 ± 6.34. Memory, executive function and visuospatial function were the three domains of impairment with the highest rates, 96.0%, 70.0%, 56.0%, respectively. The majority of MCI patients had deficits in three or more domains (62.0%). The average score of the Moca test was 20.48 ± 2.32. Delayed word recall (84.0%), delayed picture recall (86.0%), clock drawing test (78.0%), backward list of number (56.0%), frontal lobe assessment (38.0%) were the tests with the highest rate of abnormalities. The location of infarction in both cerebral hemispheres (42.0%), subcortical (68.0%) and frontal lobe infarction (36.0%) was the most common lesion location. Conclusion: Post-cerebral infarction mild cognitive impairment includes impairment in many different cognitive domains, of which the most affected are memory, visuospatial and executive functions. Brain MRI lesions are also varied with more infarcts in the subcortex and hemispheres