KHẢO SÁT CÁC ĐẶC ĐIỂM LÂM SÀNG VÀ CẬN LÂM SÀNG CỦA BỆNH NHÂN VIÊM NỘI TÂM MẠC NHIỄM KHUẨN NHẬP VIỆN TIM TRONG CÁC NĂM 2021-2023

Abstract

Aim of the study: To summarize the characteristics and response to antibiotic therapy of patients with infective endocarditis (IE) treated at the Heart Institute, to define whether the European Society of Cardiology (ESC) recommendations can be applied to vietnamese patients. Patients and methods: Cross-sectional study in patients admitted to the Heart Institute from 01/01/2021 to 31/12/2023 with a diagnosis of IE. Results: 178 patients (119 men, mean age 46,5 ± 17,2 years) were included. 16,3% had rheumatic valve disease, 23% had congenital heart disease, and 18,6% had prosthetic valve. Glomerulonephritis was present in 51,1%, RF in 20,8%, and embolic events in 21,9%. 115 patients (64,6%) had positive blood culture, mostly with Gram positive cocci. Most patients had favorable response to the ESC recommended empirical antibiotic therapy. 117 patients underwent cardiac surgery. In-hospital mortality was 14,6%. Conclusions: ESC recommendations should be used for the diagnosis of IE, with special focus on urine sediment, RF examination, and screening of embolic events. ESC recommendations for antibiotic therapy can be applied to vietnamese patients.