APPLYING THE FRAX TO ASESS THE FRACTURE RISK OF OSTEOPOROSISNIN PATIENTS WITH IDIOPATHIC INFLAMMATORY MYOPATHY

Thị Hồng Trần, Thị Phương Thủy Nguyễn

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Abstract

Objective: To investigate bone density in patients with autoimmune myositis and evaluate the risk of osteoporotic fractures using the FRAX model. Study Method: Cross-sectional descriptive analysis. The study involved 42 patients diagnosed with autoimmune myositis according to the criteria of Tanimoto et al., 1995, at Bach Mai Hospital's Orthopedics and Joint Center from September 2023 to June 2024. Results and Conclusion: Bone density at the lumbar spine and femoral neck in the autoimmune myositis patient group was 0.729 ± 0.165 g/cm² and 0.62 ± 0.149 g/cm², respectively. Osteoporosis prevalence in the study group was 47.6%, with 40.5% having decreased bone density and 11.9% having normal bone density. Older age, weaker muscle strength, and longer duration of autoimmune myositis were associated with higher osteoporosis risk. Prolonged corticosteroid use in treating autoimmune myositis was identified as a risk factor for osteoporosis in these patients. Among the subset of study participants with decreased bone density by DEXA, 21.4% (3/14 patients) were at risk of fractures within the next 10 years and require osteoporosis treatment.

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