NỒNG ĐỘ ACID URIC HUYẾT THANH VÀ MỘT SỐ BỆNH MẠN TÍNH Ở NGƯỜI BỆNH THẬN MẠN

Abstract

Background: Hyperuricemia is a common condition in chronic kidney disease and is also associated with hypertension, cardiovascular disease, and diabetes. However, the relationship between serum uric acid and chronic diseases such as hypertension, gout, diabetes, and metabolic syndrome in chronic kidney disease patients is still limited. Method: Cross-sectional study, collecting data on serum uric acid and accompanying diseases such as hypertension, gout, diabetes, and metabolic syndrome in chronic kidney disease patients (or with eGFR of 15-89 mL/min/1.73 m²) has been receiving outpatient treatment at Le Van Thinh Hospital and Ba Ria Hospital. Results: The majority of participants had eGFR of 60–89 mL/min/1.73 m², corresponding to stage 2 CKD. corresponding to stage 2 CKD. The highest rate of hypertension is 70%. The rate of gout, or MetS, is a third of the study population. Serum uric acid levels tend to gradually increase according to the eGFR subgroup (p<0.001). The rate of hyperuricemia accounts for the majority in gout (p<0.001). There was a difference in serum uric acid levels in the hypertensive and gout groups (p<0.05). Conclusion: This study concludes that serum uric acid levels gradually increase with the stages of CKD, and hypertension is a common condition in patients with hyperuricemia.