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CLINICAL CHARACTERISTICS AND HEMATOLOGICAL PARAMETERS CORRELATIONS BETWEEN UMBILICAL CORD BLOOD AND PERIPHERAL BLOOD IN EARLY-ONSET NEONATAL INFECTION
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Abstract
Objectives: To describe the clinical characteristics and to find the correlation of hematological parameters between umbilical cord blood and peripheral blood in early-onset neonatal infection (EOI). Methods: This was a prospective descriptive study. There were 83 neonates who had risk factors for EOI at the Department of Obstetrics and Gynecology, Hue University of Medicine and Pharmacy Hospital, from June 2023 to June 2024. Umbilical cord blood was taken for count blood cells analysis immediately after birth. Clinical and paraclinical features were monitored for 72 hours, then divided into 2 groups: 1) EOI group (n=40) and 2) non-EOI group (n=43). Results: The common clinical symptoms were tachypnea (77.5%), chest retraction (57.6%), vomiting (40.0%), poor feeding (32.5%), jaundice in 24h of life (75.6%). The white blood cell (WBC), red blood cell (RBC), Hemoglobin (Hb), Hematocrit (Hct) and platelets (PLT) in the umbilical cord blood of the EOI group were 12.65 ± 6.38 G/l; 4.29 ± 0.52 T/l; 152.77± 19.12 g/l; 46.89± 5.77%; 198.98 ± 96.74 G/l. There was a positive correlation between the WBC, neutrophils, lymphocytes, Hb, MCV, Hct, and PLT between umbilical cord blood and peripheral blood in the EOI group (p < 0.001). Conclusion: The symptoms of EOI were various. There was a statistically significant positive correlation between some hematological parameters of umbilical cord blood and peripheral blood in EOI.
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Keywords
early-onset infection, umbilical blood, hematological parameters
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