ASSESSMENT OF ASTHMA CONTROL IN CHILDREN WITH ASTHMA COMBINED WITH ALLERGIC RHINITIS: A SINGLE-CENTER RETROSPECTIVE

Trần Ngọc Hiếu Nguyễn, Thái Sơn Phạm, Kim Lâm Hoàng, Thị Quế Phạm, Văn Duy Trần, Thị Bích Liên Lê, Mạnh Cường Nguyễn

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Abstract

Objectives: To evaluate the role of CARATkids questionnaires for assessment of asthma control in children with asthma combined with allergic rhinitis. Subjects and methods: Case series study of  128 childhood asthma combined with allergic rhinitis aged between 6 to 15 years old were examined, lung function tests and asthma control at the initial visit, after one month of treatment. Asthma control was assessed using ACT questionnaires and CARATkids questionnaires. This study was performed at the Pediatric Departments, Military Hospital 103, Vietnam Military Medical University. Results: The mean score of CARATkids at the initial visit of the uncontrolled group was 9.3 ± 2.0 compared to 6,2 ± 1,6 in the controlled group, p <0.001. There were negative correlations between CARATkids score and lung function indexes such as PEF (r=-0,189, p=0,03), FEV1 (r= -0,245, p=0,006), FEV1/FVC (r=-0,284, p=0,001) and ACT (r=-0,759, p<0,001). After 1 month of treatment, CARATKid's score was  3,6 ± 2.1, lower than the initial visit (8,3 ± 2.4), p<0.05. With CARATkids = 4.5 points, this limit defined uncontrolled asthma in children with asthma and allergic rhinitis; with the AUC: 0.953, the sensitivity was 100%, the specificity was 78.6%, p<0.001. Both ACT and CARATkids questionnaires are valid for assessing asthma control in children. Conclusion: CARATKids is a valid tool for assessing the control of allergic rhinitis and asthma in children.

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References

Bousquet, J. and et. al, Allergic rhinitis and its impact on asthma (ARIA) 2008. Allergy 2008. 63: p. 8-160.
2. Thomas, M. and et. al, Asthma-related health care resource use among asthmatic children with and without concomitant allergic rhinitis. Pediatrics 2005. 115(1): p. 129-134.
3. Schatz, M., et al., Asthma Control Test: reliability, validity, and responsiveness in patients not previously followed by asthma specialists. J Allergy Clin Immunol, 2006. 117(3): p. 549-56.
4. Linhares, D.V., et al., Validation of control of allergic rhinitis and asthma test for children (CARATKids)–a prospective multicenter study. Pediatric Allergy and Immunology, 2014. 25(2): p. 173-179.
5. Batmaz, S.B., S.A. Tokgöz, and J.A. Fonseca, Validity and the reliability of the Turkish version of the control of allergic rhinitis and asthma test for children (CARATKids). Journal of Asthma, 2019. 56(11): p. 1231-1238.
6. Ngô Quý Châu, V.T.Q., Khuyến cáo chẩn đoán và điều trị hen kèm viêm mũi dị ứng. Nhà Xuất Bản Y Học, 2016.
7. (GINA), G.I.f.A., Global strategy for asthma management and prevention. 2019.
8. Emons, J., et al., Use of the Control of Allergic Rhinitis and Asthma Test (CARAT kids) in children and adolescents: Validation in Dutch. Pediatric Allergy and Immunology, 2017. 28(2): p. 185-190.
9. Lê Thị Minh Hương, L.T.H., Một số đặc điểm dịch tễ học lâm sàng hen phế quản trẻ em tại Bệnh viện Nhi Trung ương, năm 2011. Y Học Thực Hành, 2013. 870(5): p. 119-21.
10. Togias, A., et al., Rhinitis in children and adolescents with asthma: Ubiquitous, difficult to control, and associated with asthma outcomes. Journal of Allergy and Clinical Immunology, 2019. 143(3): p. 1003-1011. e10.