LỰA CHỌN THUỐC KHÁNG ĐỘNG KINH CHO NGƯỜI BỆNH ĐỘNG KINH SAU ĐỘT QUỴ NÃO

Abstract

Objective: To describe the clinical and paraclinical characteristics and evaluate some antiepileptic drug options in patients with post-stroke epilepsy. Methods: A cross-sectional descriptive study was conducted on 85 patients diagnosed with post-stroke epilepsy at the Neurology Center, Bach Mai Hospital, from January 2023 to June 2024. Results: The average age was 63.11 ± 12.80 years, with the most common age group for post-stroke epilepsy being 60-75 years, accounting for 47 cases (55.3%). Male patients made up 69.4% of the cases. Brain MRI showed that the majority of lesions were found in two or more lobes, accounting for 51.8%. Seizures most commonly occurred 6-12 months after the stroke, making up 57.6% of cases. Focal seizures were the most common, accounting for 81.2%, with generalized focal seizures being the predominant type, observed in 48 out of 85 patients (56.5%). Of the 82 out of 85 patients treated with monotherapy using antiepileptic drugs (96.5%), 47 patients were treated with Levetiracetam (55.3%) and 20 patients with Carbamazepine (23.5%). In the studied group, 98.8% of patients were able to control seizures and were discharged. Conclusion: Post-stroke epilepsy (PSE) is commonly observed in individuals over 60 years old, with clinical manifestations primarily in the form of focal seizures. PSE has a high seizure control rate and can be stably managed with monotherapy using antiepileptic drugs.