KHẢO SÁT SỰ KHÁC BIỆT VỀ ĐẶC ĐIỂM DỊCH TỄ, LÂM SÀNG CỦA BỆNH NHÂN VẢY NẾN ĐIỀU TRỊ BẰNG THUỐC SINH HỌC SO VỚI NHÓM SỬ DỤNG CÁC PHƯƠNG PHÁP ĐIỀU TRỊ KHÁC

Abstract

Objective: To investigate the epidemiological and clinical characteristics of patients with moderate-to-severe psoriasis vulgaris treated with biological agents, compared to those using other treatment methods. Subjects and Methods: A case series study was conducted at HCMC Hospital of Dermatology and Venereology, involving 253 participants from March 2024 to June 2024. Results: Patients receiving biologics were generally older, had a higher male-to-female ratio, and had higher educational and income levels than those in other treatment groups. Biologic treatment was associated with a longer disease duration and significantly greater treatment efficacy, evidenced by lower PASI, BSA, and DLQI scores. In contrast, patients in the non-biologic treatment group predominantly used topical medications (97.5%) and conventional systemic therapies (60.8%). The primary barrier to biologic therapy was its high cost, as reported by 75.8% of patients. Conclusion: Biologics were shown to be an effective treatment option, leading to high patient satisfaction. The study highlighted notable differences in socioeconomic status and treatment outcomes between patients treated with biologics and those using other therapies.