ĐÁNH GIÁ TĂNG TRƯỞNG VÀ TÌNH TRẠNG CHẬM TĂNG TRƯỞNG NGOÀI TỬ CUNG Ở TRẺ SƠ SINH NON THÁNG TẠI BỆNH VIỆN NHI ĐỒNG 1

Abstract

Background: Nowadays, with advances in the field of neonatal care, more preterm neonates are surviving and growing with suitable nutritional support. Extrauterine growth restriction (EUGR) causes serious consequences. Knowing the growth patterns and the prevalence of EUGR in premature neonates is crucial in clinical practice. Objectives: Description of growth and determine the prevalence of EUGR in preterm neonates at Children's Hospital 1. Methods: Cross-sectional study from December 2023 to September 2024 at Children's Hospital 1. Results: The rate of low birth weight premature infants was 8.5% (8/94 infants). The rate of extrauterine growth retardation at the time of NICU discharge and hospital discharge was 47.9% and 61.7%, respectively. The velocity of weight gain, length, and head circumference during NICU and post-NICU stay was 6.9, 8.9g/kg/day, 0.8, 1.0 cm/week for length and 0.6, 0.7 cm/week for head circumference, respectively. The amount of protein provided in the first and second weeks had median (IQR) of 2.1 (1.8, 2.3) and 2.9 (2.5, 3.2) g/kg/day, respectively. Risk factors for extrauterine growth restriction were small gestational age with Odds Ratio (OR) 0.4 (0.3-0.5), early neonatal infection OR 4.5(1.8-10.8) and late infection OR 3.9(1.6-9.6), enteral milk intolerance with OR 4.9 (1.28-19.1), gastrointestinal surgery with OR 2.3(1.0-5.6) and chronic lung disease with 2.3(1.0-5.6). Conclusion: Small gestational age, early and late neonatal infections, enteral milk intolerance, gastrointestinal surgery and chronic lung disease are risk factors for extrauterine growth restriction in preterm infant