VALUE OF SOME CONVENTIONAL COAGULATION TESTS AND ROTEM TEST IN CIRRHOSIS PATIENT WITH BLEEDING

Thị Kiều My Trần, Việt Dũng Nguyễn, Minh Tân Đặng, Ngọc Thạch Phạm

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Abstract

Objective: To evaluate the value of some conventional coagulation tests and ROTEM test in cirrhosis patient with bleeding. Subjects and methods: Cross-sectiona descriptiv an retrospectiv study, 136 cirrhosis patients hospitalize at NHTD from 2019 to 2022 were enrolled in this study. Results: 136 patients had an average age of 50.9 ± 11.5 years, 78% were male; Clinical bleeding rate was 39%; There was no statistically significant difference in PT%, rAPTT, Fibrinogen between the 2 groups with and without bleeding, while the platelet count in the bleeding group was statistically significantly lower  (p = 0.045); Clot amplitude indices on ROTEM were different between the 2 groups of bleeding and non-bleeding (P < 0.05), but CT index was not. Patients with hypocoagulation on ROTEM had a bleeding rate of 41.3%, statistically significantly higher than the group with normal ROTEM results (p=0.047). Conclusion: Abnormal conventional coagulation test do not predict the risk of bleeding in cirrhosis patient. A normal ROTEM test can help excludes reasons bleeding due to coagulopathy in patients with Abnormal conventional coagulation test

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References

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