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Date Published: 24/10/2021
Abstract Views: 435
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DOI: https://doi.org/10.51298/vmj.v506i2.1244
Issue
Vol. 506 No. 2 (2021)
Section
Các bài báo
How to Cite
Văn Trọng, N. ., Quốc Duy, N. ., Chính Đại, L. ., & Văn Quảng, L. . (2021). RESULTS OF TREATMENT FOR cT1-2N0M0 CARCINOMAS OF THE FLOOR OF MOUTH. Vietnam Medical Journal, 506(2). https://doi.org/10.51298/vmj.v506i2.1244

RESULTS OF TREATMENT FOR cT1-2N0M0 CARCINOMAS OF THE FLOOR OF MOUTH

Nguyễn Văn Trọng1,, Ngô Quốc Duy2, Lê Chính Đại1, Lê Văn Quảng1,2
1 Hanoi Medical University
2 K Hospital

Main Article Content

Abstract

Objectives: This study was conducted to report the recurrence rate, the survival rate in mouth floor cancer patients staged cT1-2N0M0 and analyze the prognostic factors associated. Patients and methods: A retrospective, descriptive study on 65 patients with cT1-2N0M0 floor of mouth cancer were treated in K hospital from 01/2015 to 12/2019. Results: Majority were under 60 years old (73,8%); male/female ratio: 8,3/1; 34 patients were staged T1 (52,3%); occult lymph node metastasis rate: 32,3%. Recurrences were diagnosed in 21 patients (32,3%), the nodal and local-nodal recurrence rate were 57,1% and 23,8%, respectively. Tumor stage and occult lymph node metastasis were statistically associated with the recurrence (p=0,034 and p=0,001, respectively). The 5-year DFS and OS rates were 62,3% and 74%, respectively. The mean DFS and OS time was 45,08 months and 52,03 months, respectively.  Analysis of associations between DFS, OS revealed significance for tumor stage, lymph node status, and post-operative stage.Conclusions: Tumor size and occult lymph node metastasis were statistically associated with recurrence. Tumor size, nodal status and stage were associated with DFS and OS, but only nodal status was showed to be an independent risk factor.

Article Details

Keywords

floor of mouth cancer, cT1-2N0M0, recurrence, DFS, OS

References

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