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Issue: Vol. 506 No. 2 (2021)
Section: Các bài báo
DOI: 10.51298/vmj.v506i2.1255
Date Published: 28/09/2021
Views 399
Downloads 323
How to Cite
Thị Ngà, Đ., Doãn Kỳ, T., Anh Tuấn, N., Đình Châu, N., Quang Biểu, B., Thanh Bình, M., Trường Giang, Đ., Văn Thái, N., & Tiến Thịnh, N. (2021). EFFICACY AND SAFETY OF STEREOTACTIC BODY RADIOTHERAPYFOR TREATMENT OF ADVANCED HEPATOCELLULAR CARCINOMA WITH PORTAL VEIN THROMBOSIS. Vietnam Medical Journal, 506(2). https://doi.org/10.51298/vmj.v506i2.1255

EFFICACY AND SAFETY OF STEREOTACTIC BODY RADIOTHERAPYFOR TREATMENT OF ADVANCED HEPATOCELLULAR CARCINOMA WITH PORTAL VEIN THROMBOSIS

Đinh Thị Ngà1, Thái Doãn Kỳ1, , Nguyễn Anh Tuấn1, Nguyễn Đình Châu1, Bùi Quang Biểu1, Mai Thanh Bình1, Đinh Trường Giang1, Nguyễn Văn Thái1, Nguyễn Tiến Thịnh1
1 108 Military Central Hospital

Main Article Content

Abstract

Objective: To evaluate the initial results and toxicity of stereotactic body radiotherapy (SBRT)for treatment ofHepatocellular Carcinoma (HCC) with Portal Vein Thrombosis (PVT). Methods: A prospective study on 31 HCC patients with main branch or trunk portal vein thrombosis were treated by SBRT; follow-up between July, 2018 to June, 2021at Military Central Hospital 108. Ojective Response Rate (ORR), Overall Survival (OS) andtoxicitywere evaluated andanalyzed. Results: The objective response rate after 3 months and 6 months were 67.7% and37.9%, respectively.The median Overall Survival was 13 months. The overall survival rate after 6 months, 1- year was 93.5% and 54.8%. Most of  toxicities were grade 1or2 including thrombocytopenia, liver enzyme elevation, abdominal pain. There was no case of treatment-related death. Conclusion: SBRT is a safe and effective treatment option for advancedHCC with PVT

Keywords

Stereotactic body radiotherapy, Hepatocellular Carcinoma, Portal vein thrombosis

Article Details

References

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