MỘT SỐ CHỈ SỐ ĐÔNG CẦM MÁU VÀ MỐI LIÊN QUAN VỚI TÌNH TRẠNG DI CĂN TỦY XƯƠNG Ở BỆNH NHÂN UNG THƯ DẠ DÀY VÀ UNG THƯ THỰC QUẢN NGUYÊN PHÁT KHÔNG ĐỒNG MẮC BỆNH LÝ HUYẾT HỌC ÁC TÍNH TẠI VIỆN HUYẾT HỌC – TRUYỀN MÁU TRUNG ƯƠNG GIAI ĐOẠN 2020 – 2022

Abstract

Objectives: (1) Describe some hemostatic indices in primary gastric cancer or esophageal cancer patients without malignant hematological disease. (2) Describe the relationship between bone marrow metastases and disseminated intravascular coagulation in the group of subjects at the National Institute of Hematology - Blood Transfusion over the period from 2020 to 2022.  Methods and materials: 31 patients admitting the first time at the time and research location, already been diagnosed with gastric cancer or esophageal cancer before admission and without concurrent malignant hematological diseases. Results: Age group ≥55 years old and male gender dominates other groups. 45,2% of the patients suffer from disseminated intravascular coagulation (DIC). The risk of bone marrow metastases and total DIC score follow logistic regression correlation, with each point increased in DIC score increasing correlating with 4,88 times of metastasis of primary cancer cells to bone marrow. Conclusion: The risk of bone marrow metastases and the total DIC score according to ISTH in the study had a logistic regression correlation, each 1 DIC point increased the risk of metastasis of primary cancer cells to the bone marrow by 4,88 times. Screening for malignant hematological disease, bone marrow metastatic cancer and disseminated intravascular coagulation should be carried out routinely, all at once and as soon as possible for all patients with stomach and esophageal cancer to choose the most suitable treatment for patients.