THE ASSOCIATION BETWEEN ADIPOQ rs1501299 AND TYPE 2 DIABETES IN VIETNAMESE POPULATION

Trần Quang Nam1, Steven Truong2, Hoàng Khánh Chi3, Lê Hoàng Bảo3, Đinh Ngô Tất Thắng3, Trần Viết Thắng1, Trần Văn Lượng3, Mã Tùng Phát1, Mai Phương Thảo1, Đỗ Đức Minh1,
1 University of Medicine and Pharmacy at Ho Chi Minh City
2 Department of Biological Engineering, Massachusetts Institute of Technolo
3 University Medical Center Ho Chi Minh City

Main Article Content

Abstract

Background: Genetic factor plays an important role in pathophysiology of type 2 diabetes. In this study, we evaluated the association between ADIPOQ rs1501299 and type 2 diabetes in Vietnamese population. Objectives and methods: In this cross sectional study, 376 type 2 diabetic patients and 392 controls were recruited and genotyped for ADIPOQ rs1501299 by real-time PCR. Results: ADIPOQ rs1501299 was not statistically associated with type 2 diabetes in Vietnamese population by different statistical models. The rs1501299 carriers do not increase the risk of developing type 2 diabetes. Conclusion: ADIPOQ rs1501299 is not associated with type 2 diabetes mellitus in Vietnamese population.

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References

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