PROFILES OF ANTIMICROBIAL RESISTANCE OF PSEUDOMONAS AERUGINOSA ISOLATED FROM SPUTUM OF PATIENTS AT MILITARY HOSPITAL 103 IN 2022

Hạ Long Hải Lê, Văn An Nguyễn

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Abstract

Objective: To investigate the antibiotic resistance pattern of Pseudomonas aeruginosa isolated from patients at the Military Hospital 103 in 2022. Subjects and Methods: A cross-sectional studt was conducted on P. aeruginosa isolates from sputum samples of patients at Military Hospital 103 in 2022. Results: Of the 510 pathogens isolated from sputum samples of patients at Military Hospital 103 in 2022, there were 101 (19.8%) P. aeruginosa strains. Most of P. aeruginosa strains were isolated from patients ≥ 66 years old (50.5%) and males (77.2%). Antibiogram analysis showed high resistance rates of P. aeruginosa to most common antibiotics (64.6–79.6%), except for colistin (100% sensitivity). The antibiotic resistance rates of P. aeruginosa isolated from patients in the Intensive Care Unit (ICU) were 3-4 times higher than in other departments for most tested antibiotics in this study. The study indicated that the rates of antibiotic resistance (AMR) and multidrug resistance (MDR) were high, at 84.2% and 71.3%, respectively. Conclusion: Our study revealed that most P. aeruginosa strains were isolated from patients ≥ 66 years old (50.5%) and males (77.2%). The rate of AMR and MDR of P. aeruginosa was very high, especially in the isolates of patients in the ICU. The study indicated the necessity for implementing strict infection control measures and developing effective treatment regimens to improve the quality of treatment and to fight against antimicrobial resistance of P. aeruginosa

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References

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