CÁC RỐI LOẠN VỀ HUYẾT HỌC Ở BỆNH NHÂN NGỘ ĐỘC CẤP

Abstract

Objective: To describe the characteristics of hematological disorders in patients with acute poisoning and identify common toxins causing hematological disorders. Subjects and methods: An observational study included 161 acute poisoned patients with hematological disorders treated at the Poison Control Center of Bach Mai Hospital from January 2023 to June 2024. Results: Among acute poisoned patients with hematological disorders, male were more common (55.9%), most patients were in working age (79.5%) and the majority of acute poisoning was due to suicide (60.3%). Leukocytosis was common (55.3%) with an average white blood cell count of 15.9 ± 2.3 G/L, only 2.5% of acute poisoning caused leukopenia. 19.9% ​​of patients had anemia, mainly mild anemia. 14.3% of patients had platelet disorders, mostly mild thrombocytopenia. 49.1% of patients had extrinsic coagulation disorders, 9.3% had DIC, 12.4% had increased D-dimer, 14.9% had fibrinogen disorders. The most common causes were poisoning by pesticides, viper bites and medications. Conclusion: The study showed the main characteristics of hematological disorders in patients with acute poisoning and common toxins causing hematological disorders.