ĐẶC ĐIỂM LÂM SÀNG, CẬN LÂM SÀNG VÀ KẾT QUẢ ĐIỀU TRỊ LAO PHỔI CHẨN ĐOÁN DỰA TRÊN BẰNG CHỨNG MÔ BỆNH HỌC

Abstract

Objectives: Describe some clinical and paraclinical characteristics of pulmonary tuberculosis patients diagnosed based on histopathological evidence and evaluate treatment results after 2 months of attack in the patient group studied at the Hospital. Central Lung Institute. Subjects and methods: Descriptive study with longitudinal follow – up retrospective combined with prospective on 66 patients with lesions suspected of pulmonary tuberculosis on X-ray and CT without evidence of tuberculosis bacteria and underwent lung biopsy for histopathological diagnosis of pulmonary tuberculosis lesions. and inpatient treatment at the Central Lung Hospital retrospectively from January 2023 to the end of June 2024. Results: Average age was 48.5 ± 16.6 years; 41 cases are male, accounting for 62.1%. The rate of self-employment is the highest, 22/66 (33.3%); 25,8% of patients live in rural areas. Average. BMI is 20.7±2.6. The rate of smoking was 43.9% and history of chronic disease was 45.5%. The study subjects' systemic and functional symptoms after 2 months of intensive treatment decreased: Fatigue from 78.8% - 7.6%; Fever from 30.3% - 1.5%; Chest pain 71.2% - 10.6%; Prolonged cough 71.2% - 4.5%; Coughing up blood, difficulty breathing 0%. There were 8 cases of MGIT with sputum (+) initially reduced to 1 case of MGIT with sputum (+). The size of the lesion, both horizontal diameter and anterior and posterior diameter, was different before and after treatment, the difference was statistically significant with p < 0.05. Conclusion: The study subjects' systemic and functional symptoms after 2 months of intensive treatment were significantly reduced. There is a relationship between the size of the lesion, both the horizontal diameter and the anterior-posterior diameter, which are different before and after treatment.