EFFICACY OF TREATMENT FOR PAINFUL SYMPTOMS AMONG HOSPITALIZED ELDERLY DEPRESSION

Vũ Thị Lan1,2,, Nguyễn Văn Tuấn1,2
1 Hanoi Medical University
2 National Mental Health Institute, Bach Mai Hospital

Main Article Content

Abstract

Objective: To evaluate the effectiveness of treatment for elderly depression with pain. Subjects and methods: Using a cross-sectional descriptive method, analyzing the effectiveness of treatment for pain by directly interviewing and testing VAS, GDS on 50 the elderly in-patients diagnosed major depressive disorder having pain at the National Institute of Mental Health –Bachmai Hospital, using VAS, GDS for these patients, and checking records of patients. Results: 84.0% of patients used a combination of antidepressants, neuroleptics and tranquilizers; the number of pain sites reduced by 2.26 ± 1.45, the VAS pain level decreased by 3.2 ± 0.99 points, the level of depression on the GDS scale reduced by 7.3 ± 7.21 points, there was a statistically significant difference. there was no difference bettwen pain relief in the levels of depression, anticholinergic was the most common side effects (52.0%). Conclusion: Majority of patients used the combination of drugs, pain symptoms improved significantly and depression was reduced together. However, there was no difference bettwen pain relief in the degrees of depression. The most common adverse drug reaction in elderly depression is anticholinergic.

Article Details

References

1. Zivin K, Wharton T, Rostant O (2013). The Economic, Public Health, and Caregiver Burden of Late-life Depression. Psychiatric Clinics of North America, 36(4), 631-649.
2. Fiske A, Wetherell JL, Gatz M (2009). Depression in Older Adults. Annu Rev Clin Psychol, 5(1), 363-389.
3. Silva MR da, Ferretti F, Pinto S da S et al (2018). Depressive symptoms in the elderly and its relationship with chronic pain, chronic diseases, sleep quality and physical activity level. Brazilian Journal Of Pain, 1(4).
4. Zis P, Daskalaki A, Bountouni I, et al (2017). Depression and chronic pain in the elderly: links and management challenges. Clin Interv Aging, 12:709-720.
5. Raskin J, Wiltse CG, Siegal A, et al (2007). Efficacy of duloxetine on cognition, depression, and pain in elderly patients with major depressive disorder: an 8-week, double-blind, placebo-controlled trial. Am J Psychiatry, 164(6).
6. Demyttenaere K, Reed C, Quail D, et al (1981). Presence and predictors of pain in depression: Results from the FINDER study. Journal of Affective Disorders, 125(1-3):53-60.
7. Boss GR, Seegmiller JE(2021). Age-Related Physiological Changes and Their Clinical Significance. West J Med. 135(6):434-440.