ĐẶC ĐIỂM LÂM SÀNG VÀ CẬN LÂM SÀNG CỦA U LYMPHO KHÔNG HODGKIN TẾ BÀO ÁO NANG TẠI BỆNH VIỆN K

Abstract

Objective: Describe the clinical and paraclinical characteristics of Mantle cell lymphoma. Subjects and methods: A cross-sectional descriptive prospective study was conducted on 73 patients with mantle cell lymphoma treated with RDHAP/RCHOP or RB/RBAC regimens at the Hematologic Oncology Department, K Hospital from May 2019 to May 2024. Results: The average age was 60; The male/female ratio was ~2.17; PS 0 accounted for 87.7%. Syndrome B occurred in 27.4% of patients; Patients admitted to the hospital due to lymphadenopathy accounted for 64.4%; The median lesion size was 4.0 cm. Bulky lesions accounted for 17.8%; The most common lymph node lesions were abdominal lymph nodes (84.9%) and head and neck lymph nodes (72.6%); There were 48 patients with extranodal lesions accounting for 65.8%, of which the highest rate of lesions in the colon was 27.4% and the stomach was 24.7%; the rate of low or intermediate MIPI risk group was 32%; high risk was 36%; patients were mainly in stage 3 or 4 accounting for 86%. Conclusion: The characteristic clinical features of mantle cell lymphoma support doctors in the process of early diagnosis and timely and appropriate treatment selection for these patients.