A SYSTEMATIC REVIEW OF THE TREATMENT FOR ALLERGIC RHINITIS USING CORTICOID NASAL SPRAY
Main Article Content
Abstract
Background: Allergic rhinitis (AR) affects approximately 400 million people worldwide and is one of the most common chronic diseases globally. Medical treatment with drugs is the basic method to control the symptoms of allergic rhinitis and nasal corticosteroids are considered the first choice. Objective: To review recent studies and reports on nasal corticosteroid sprays for the treatment of allergic rhinitis. Research method: Synthesize all clinical studies on nasal Corticoid sprays for the treatment of AR, from 2014 to 2024, published in online databases: Pubmed, Goggle Scholar, University of Medicine and Pharmacy libraries and Medical journals in Vietnam. Results: A total of 305 studies were searched. Finally, there were 13 studies suitable for full-text analysis and data extraction. Many methods have been applied to evaluate the effectiveness of treatment such as TNSS (Total Nasal Symptom Score), TOSS (Total Orcular Symptom Score), VAS (Visual Analogic Scale), RQLQ (Rhinoconjunctivitis Quality of Life Questionnaire), inferior turbinate hypertrophy, nasal mucosal secretions, nasal resistance, nasal airflow, pulmanary function test, eosinophil and mast cell in nasal fluid were all improved. In addition, the concentration of IgE, IgG in plasma, skin prick test, Matocyte degranulation reaction were not affected. Long-term use of the drug (1 year) when treating PAR in children does not affect urinary Cortisol concentration, affects short-term growth and there is no clear evidence that the drug affects long-term growth. Conclusion: Nasal corticosteroid spray is a good method to improve the symptoms of allergic rhinitis.
Article Details
Keywords
Allergic rhinitis, Seasonal Allergic Rhinitis, Perennial Allergic Rhinitis, Corticoid nasal spray
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