Backgrounds: The cervical spine is one of the regions with a rather complex structure with many small components creating a complex and performing many important functions in the human body. Problems in the neck area can significantly affect an individual's quality of life and their ability to carry out daily activities and tasks. Pain points often appear in the neck area and spread to the shoulder blades and arms, causing discomfort and affecting the patient's function. Many studies have shown that pain points appear more along the muscle rows of the upper trapezius muscle, one of three muscles in the large trapezius muscle mass that runs along the cervical spine down to the shoulder blades and thoracic spine. Myofascia Pain Syndrome can occur in the trapezius muscle when there is excessive tension or the development of trigger points in the fascia. This can lead to localized pain, and limited range of motion in the affected muscle. In Physical Therapy, there are many interventions on these pain points to improve pain such as: stretching, soft tissue movement, ultrasound, laser or using shock waves. On the pain points of the upper trapezius muscle, many studies around the world apply shock waves as a potential treatment method for myofascial pain syndrome, targeting trigger points and muscle tension areas to reduce pain and Improve muscle function. In Vietnam, shock waves in physical therapy have been widely used, but there have not been many studies in Vietnam evaluating its effectiveness on domestic subjects, mainly based on medical evidence. of foreign countries. For the above reason, the research team wanted to find the effectiveness of shock waves in improving pain points on the muscle, specifically pain points on the upper trapezius muscle in subjects with problems. in the neck and shoulder area. Objectives: To evaluate the effectiveness of extracorporeal shock waves on trigger points of the upper trapezius muscle during 05 weeks. Methods: Clinical quasi-experimental studies are used on subjects with neck and shoulder defects and pain points on the upper trapezius muscle. The study recorded information about socio-demographic characteristics, disease status, and pain pressure thresholds – PPT through a set of direct interview questions and pain assessment tools. T-test, Mann - Whitney, ANOVA test analyzes variables to find out the relevance and statistical significance of the variables. Univariate and multivariate linear regression aimed to determine the relationship between many factors to the pain level of the subjects. Results: The study recorded results on 45 subjects, including 24 subjects in the standard intervention group and 21 subjects in the minimal intervention group. The changes in PPT measurements recorded in the standard intervention group before and after intervention was 477 ± 228 and 1029 ± 283, respectively, with p < 0.001. In addition, the minimal intervention group recorded PPT measurements before and after intervention of 604. ± 277 and 822 ± 385 with p=0.01. Therefore, the study also recorded that the NDI value of the standard intervention group changed significantly from 12.83 ± 5.7 before intervention to 6.58 ± 4.10 after intervention with p < 0.001, NRS index also from 6.04 ± 1.6 to 2.37 ± 1.43 with p<0.001. Also, we recorded results in the minimal intervention group with a slight decrease in the NDI index from 12.38 ± 4.03 before intervention to 10.28 ± 5.71 after intervention with p = 0.04. Similarly, the NRS index also recorded a slight decrease from 6.2 ± 1.4 and 3.76 ± 3.76 ± 2.16 with p<0.001 before and after intervention, respectively. Conclusions: The study evaluated the effectiveness of releasing pain in subjects with trigger points on the upper trapezius muscle clearly through shock wave intervention with the recommended duration of 05 consecutive treatments in 01 time/week, the intensity of using is 120J with 1500 shocks and frequency of 16Hz. In addition, the study also shows that shock wave intervention can help subjects improve pain and functional activities of the neck and shoulder area through improving NDI scores and NRS scales