THE VALUE OF 640-SLICE COMPUTED TOMOGRAPHY IN DIAGNOSING CORONARY ARTERY STENOSIS AT HOA HAO – MEDIC CAN THO GENERAL HOSPITAL

Dinh Nguyễn, Văn Vinh Chu, Thị Kiều Oanh Nguyễn, Phi Sơn Dương, Văn Triệu Trần, Như Tiến Trần, Thị Thanh Hằng Nguyễn

Main Article Content

Abstract

Background: A 640-slice coronary computed tomography angiography has been demonstrated to be a highly promising non-invasive diagnostic method for detecting coronary artery stenosis. In Vietnam, research in this field remains scarce. Objectives: The study aims to evaluate the diagnostic value of 640-slice computed tomography in coronary artery disease. Materials and methods: This is a descriptive cross - sectional study with an analytical component, conducted on 390 patients suspected of having coronary artery lesions. These patients sought consultation and treatment at Hoa Hao – Medic Can Tho General Hospital from July 2023 to October 2024. Results: The 640-slice computed tomography demonstrated near-perfect sensitivity, specificity, positive predictive value, negative predictive value, and accuracy, with an excellent kappa coefficient in diagnosing significant stenosis in the LM, LAD, LCx, and RCA branches, as well as at the segmental level of the coronary arteries. The Bland-Altman plot indicated a low level of discrepancy between the two methods in assessing significant stenosis of the LM branch. Conclusion: The 640-slice computed tomography exhibited high sensitivity, specificity, negative predictive value, positive predictive value, and accuracy in diagnosing significant coronary artery stenosis when evaluating coronary branches and segments

Article Details

References

1. Guzman Castillo M, Gillespie DO, Allen K, et al. Future declines of coronary heart disease mortality in England and Wales could counter the burden of population ageing. PLoS One. 2014; 9(6): e99482. doi:10.1371/journal. pone.0099482
2. Jebari-Benslaiman S, Galicia-García U, Larrea-Sebal A, et al. Pathophysiology of Atherosclerosis. Int J Mol Sci. 2022;23(6):3346. doi:10.3390/ijms23063346
3. Kaiser C, Bremerich J, Haller S, Brunner-La Rocca HP, et al. Limited diagnostic yield of non-invasive coronary angiography by 16-slice multi-detector spiral computed tomography in routine patients referred for evaluation of coronary artery disease. Eur Heart J. 2005;26(19):1987-1992. doi:10.1093/eurheartj/ehi384
4. Phạm Gia Khải, Nguyễn Lân Việt, Nguyễn Thị Thu Hoài. Tình hình các bệnh lý tim mạch tại Viện tim mạch Việt Nam 2003–2007. Tạp chí Tim mạch học. 2011;59:949-954.
5. Lei Z, Han P, Xu H, Yu J. Application study of 640-slice computed tomography low dose coronary angiography. Digit Med. 2015;1(1):28-33. doi:10.4103/2226-8561.143948
6. Leschka S, Alkadhi H, Plass A, Desbiolles L, Grünenfelder J, Marincek B, Wildermuth S. Accuracy of MSCT coronary angiography with 64-slice technology: first experience. Eur Heart J. 2005;26(15): 1482-1487. doi:10.1093/eurheartj/ ehi261
7. Martuscelli E, Romagnoli A, D’Eliseo A, et al. Accuracy of thin-slice computed tomography in the detection of coronary stenoses. Eur Heart J. 2004; 25(12): 1043-1048. doi:10.1016/j.ehj.2004. 03.024
8. Mowatt G, Cummins E, Waugh N, et al. Systematic review of the clinical effectiveness and cost-effectiveness of 64-slice or higher computed tomography angiography as an alternative to invasive coronary angiography in the investigation of coronary artery disease. Health Technol Assess. 2008;12(7):9-143.
9. Raff GL, Abidov A, Achenbach S, et al. SCCT guidelines for the interpretation and reporting of coronary computed tomographic angiography. J Cardiovasc Comput Tomogr. 2009;3(2):122-136. doi:10.1016/j.jcct.2009.01.001
10. Reiber JH, Tu S, Tuinenburg JC, et al. QCA, IVUS and OCT in interventional cardiology in 2011. Cardiovasc Diagn Ther. 2011;1(1):57-70. doi:10.3978/j.issn.2223-3652.2011.09.03