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Date Published: 26/03/2025
Abstract Views: 63
Views pdf: 29
DOI: https://doi.org/10.51298/vmj.v547i1.12833
Issue
Vol. 547 No. 1 (2025)
Section
Các bài báo
How to Cite
Lý, X. Q., Trần, N. T. L., Lê, Q. H., & Trần, T. T. (2025). OUTCOMES FOLLOWING TOTAL LARYNGECTOMY FOR ADVANCED STAGE LARYNGEAL CANCER AT UNIVERSITY MEDICAL CENTER HO CHI MINH CITY. Vietnam Medical Journal, 547(1). https://doi.org/10.51298/vmj.v547i1.12833

OUTCOMES FOLLOWING TOTAL LARYNGECTOMY FOR ADVANCED STAGE LARYNGEAL CANCER AT UNIVERSITY MEDICAL CENTER HO CHI MINH CITY

Xuân Quang Lý, Ngọc Tường Linh Trần, Quang Hưng Lê, Thanh Tài Trần

Main Article Content

Abstract

Objective: To evaluate treatment outcomes for advanced-stage laryngeal cancer patients who underwent total laryngectomy. Method: The study included all patients with T3, T4a, or T4b stage laryngeal cancer who underwent total laryngectomy at the University Medical Center in Ho Chi Minh City from 2018 to 2021. Data collection involved medical records and quality-of-life assessment using the EORTC-C30 and EORTC H&N-35 questionnaires. Results: Of 64 eligible patients, 47 completed the quality-of-life questionnaire. The mean disease-free survival was 45.3 months, with a three-year overall survival rate of 82.2%. However, quality of life decreased significantly, especially in communication ability, olfactory-gustatory function, and psychological well-being. Postoperative complications included pharyngocutaneous fistula, infection, and pneumonia. Conclusion: Total laryngectomy extended survival for advanced laryngeal cancer patients but had a substantial impact on quality of life. Interventions to improve quality of life post-surgery are essential.

Article Details

Keywords

Advanced stage laryngeal cancer, total laryngectomy.

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