ĐẶC ĐIỂM DI CĂN HẠCH Ở BỆNH NHÂN UNG THƯ PHỔI KHÔNG TẾ BÀO NHỎ ĐƯỢC PHẪU THUẬT NỘI SOI TẠI BỆNH VIỆN BẠCH MAI

Abstract

Objective: To determine the rate of lymph node metastasis and its association with various factors in patients with non-small cell lung cancer (NSCLC) undergoing endoscopic lobectomy and lymph node dissection. Methods: A descriptive, retrospective study of 74 patients diagnosed with NSCLC who underwent endoscopic lobectomy and lymph node dissection at Bach Mai Hospital between January 2023 and August 2024. Results: The disease was more prevalent in patients aged >65 years (41.9%), with a mean age of 61.8 ± 9.4 years. Most patients were male (66.2%). NSCLC was more common in the right lung (62.2%), with the upper lobe of the right lung being the most frequently affected site (32.4%). The majority of tumors were ≤3 cm in size (56.7%), adenocarcinoma type (63.5%), and non-invasive to the pleura (63.5%). Lymph node metastasis was identified in 21 of 74 patients (28.4%), with N1 metastasis in 18.9% and N2 metastasis in 9.5%. The rate of lymph node metastasis was significantly higher in patients aged 55–65 years (28.6%) compared to those aged <55 years (12.9%) or >65 years (12.9%) (p < 0.05). Lymph node metastasis correlated positively with tumor size, a statistically significant relationship (p = 0.019). There was no significant association between lymph node metastasis and factors such as gender, tumor location, pleural invasion, or histopathological type. Conclusion: Lymph node metastasis occurred in 28.4% of patients, including N1 metastasis in 18.9% and N2 metastasis in 9.5%. Lymph node metastasis was significantly associated with age and primary tumor size (p < 0.05). Other factors, including gender, tumor location, pleural invasion, and histopathological type, were not significantly associated with lymph node metastasis