HEMATOLOGICAL CHARACTERISTICS IN PATIENTS WITH LIVER CIRRHOSIS AT TRA VINH GENERAL HOSPITAL

Anh Duy Ngô, Thị Hồng Nhung Trang, Hoàng Huy Nguyễn

Main Article Content

Abstract

Objectives: The study aims to describe the characteristics of some hematological indices in patients with cirrhosis at Tra Vinh General Hospital. Subjects and methods: Descriptive cross-sectional study using retrospective data on 267 records of patients with cirrhosis who came to Tra Vinh General Hospital for examination and treatment from January 2023 to July 2024. Results: The average values ​​of RBC, HGB, HCT, PLT indices were lower than the normal limits compared to the biological reference range. The instrument for measuring red blood cell count reduced below 4 x106/µL uses 79.4%, hemoglobin concentration ≤ 109 g/L uses 67.0%, hematocrit drops below 34% uses 75.7%. In particular, up to 73.8% of patients had reduced platelet count. Conclusion: Anemia in patients with cirrhosis is still an urgent problem causing many serious consequences. Thrombocytopenia in patients with cirrhosis can lead to disorders in the coagulation process, dangerous bleeding and difficulty in surgery.

Article Details

References

1. Lê Thị Thu Hiền (2017), “Nghiên cứu một số đặc điểm lâm sàng, cận lâm sàng và chỉ số chống oxy hóa trong máu ở bệnh nhân mắc bệnh gan do rượu”, Luận án Tiến sĩ y học, Đại học Y Dược Thái Nguyên.
2. D. Ozatli and et al., "Anemias in chronic liver diseases", Taylor &Francis Online: Peer-reviewed Journals, vol. 5, no. 1, pp. 69-76, 2000.
3. I. I. Bakhriev and et al., "Features of hemogram indicators for cirrosis of the liver", ResearchGate, vol. 7, no. 2, pp. 2473-2482, 2020.
4. M. Rappai and et al., "A study of variation in haematological parameters in chronic liver disease", J. Evolution Med. Dent. Scient, vol. 8, pp. 1949-52, 2019, doi: 10.14260/jemds/ 2019/428.
5. M. Rahman and et al., "Abnormal Haematological Indices in Cirrhosis in a Tertiary Care Hospital", Saudi Journal of Medicine, vol. 7, no. 11, pp. 555-557, 2022, doi: 10.36348/ sjm.2022.v07i11.001.
6. S. Khare and et al., "To study haematological profile in patients of chronic liver disease", Internatinal Journal of Advanced Research, vol. 2, no. 8, pp. 378-81, 2015.
7. WHO (2018). "Liver cirrhosis (15+), age-standardized death rates by country" access to: https://apps.who.int/gho/data/node.main.A1092