PHÂN TÍCH TÌNH HÌNH SỬ DỤNG KHÁNG SINH TẠI BỆNH VIỆN ĐA KHOA THIỆN HẠNH - ĐẮK LẮK NĂM 2022, 2023

Abstract

Introduction: This study analyzes the current status of antibiotic use in hospitals to propose solutions for safe, rational, and effective medication use. Materials and Methodology: A cross-sectional, retrospective analysis was conducted on patient data and all antibiotics used in the hospital during 2022, 2023. The analysis included structure of drug utilization, daily defined dose (DDD), days of treatment (DOT), and various antibiotic usage monitoring indicators. Results and Discussions: Domestic antibiotics and generic antibiotics accounted for a significant proportion of consumption over the two years. 03 departments (General Surgery, Orthopedics, and Internal Medicine) had the highest value and volume of consumption. The beta-lactam group had the highest percentage of DDD (49.80% in 2022, 52.03% in 2023), with DDD/1000 population/day at 6.68 (2022) and 7.15 (2023), and DDD/100 bed/day at 38.58 (2022) and 49.27 (2023). Amoxicillin + clavulanic acid was the most widely used and consumed antibiotic. Single-drug regimens accounted for nearly 40%. The rate of injectable antibiotics was high in the Pediatrics, General Surgery, Obstetrics, and Orthopedics departments. Antibiotics requiring strict management, such as colistin, imipenem + cilastatin, meropenem, and vancomycin, were frequently used in these departments. The average duration of injectable antibiotic treatment was 4.17 days (2022) and 4.11 days (2023). Conclusion: This study provides an overview of antibiotic use at Thien Hanh General Hospital in 2022 and 2023, serving as a basis for proposing solutions to enhance the effectiveness of antibiotic management, including inventory management and antibiotic usage management programs within the hospital