ĐẶC ĐIỂM CHỨC NĂNG HÔ HẤP VÀ HRCT NGỰC Ở BỆNH NHÂN XƠ CỨNG BÌ TOÀN THỂ VÀ VIÊM CƠ VÔ CĂN CÓ BỆNH PHỔI KẼ

Abstract

Objectives: To evaluate characteristics of respiratory function and chest HRCT in patients with systemic sclerosis and idiopathic inflammatory myopathies with interstitial lung disease. Subjects and methods: A descriptive, cross-sectional study on 26 patients with systemic sclerosis and 21 patients with idiopathic inflammatory myopathies having interstitial lung disease, treated at the National Lung Hospital and Military Hospital 103 from January 2022 to April 2024. Evaluate clinical characteristics, respiratory function and chest HRCT images. Results: Patients are usually over the age of 50, mainly women (80.77% and 71.43%). The majority of patients had restrictive ventilation disorder. The most common respiratory symptoms are fine crackle and dyspnea. Respiratory failure is more common in IIM patients (p < 0.05) The most common lesion on chest HRCT is reticular (96.25 and 85.72%). Ground-glass opacities are more common in SSc patients (88.46%), while  consolidation lesions are more common in IIM patients (52.38%). NSIP lesion morphology is the most common (69.2% and 47.6%). Conclusions: Patients are usually female, middle-aged, and have dyspnea and fine crackle, restrictive ventilation disorder, reticular lesions and NSIP morphology on chest HRCT image. Patients with IIM often experience respiratory failure and lung consolidation, and have a worse prognosis.