CARCINOMA DẠNG TUYẾN NANG NGUYÊN PHÁT CỦA KHÍ QUẢN: CA LÂM SÀNG VÀ ĐIỂM LẠI Y VĂN

Abstract

Primary tracheal malignancies are exceedingly rare, with an incidence of 1.4 per million people per year, and only 16% of these cases are adenoid cystic carcinoma (ACC). About 80% of tracheal tumors are malignant, with a higher incidence in adults. Diagnosis is typically delayed because symptoms often mimic those of asthma or chronic obstructive pulmonary disease (COPD). Clinical presentation can quickly become life-threatening due to airway obstruction, requiring emergency intervention. Diagnosis is confirmed via bronchoscopy, computed tomography (CT), or magnetic resonance imaging (MRI). Definitive treatment involves tracheal resection, sometimes combined with adjuvant radiation therapy. However, complete resection is only achieved in about 40% of cases due to submucosal tumor invasion. Adjuvant radiation therapy is particularly important in patients with positive surgical margins. We present a case of a 36-year-old female diagnosed with primary adenoid cystic carcinoma of the trachea, who presented in an emergency condition due to airway obstruction, and was treated with segmental tracheal resection and end-to-end anastomosis.