TUÂN THỦ DÙNG THUỐC Ở NGƯỜI CAO TUỔI BỊ TĂNG HUYẾT ÁP: TỔNG QUAN HỆ THỐNG VÀ PHÂN TÍCH GỘP

Abstract

Introduction: Hypertension (HTN) is a prevalent medical condition, and timely treatment of HTN plays a crucial role in reducing dangerous complications. Medication adherence is considered a significant barrier to achieving optimal blood pressure control in elderly patients. Therefore, this study was conducted to provide an overview of the rate of medication adherence and the factors related to treatment adherence in the elderly. Objectives: To determine the rate of treatment adherence and the related factors influencing treatment adherence in elderly hypertensive patients through a systematic review and meta-analysis. Methods: A PRISMA-guided search was conducted on two databases Pubmed and Google Scholar. The search was performed from April 2024, and articles were selected based on predetermined criteria and assessed for quality before being included in the meta-analysis. Results: Out of 717 studies identified, 12 met the criteria and were included in the systematic review, encompassing 9,420 patients, with females comprising 53.41% aged ≥ 60 years. The meta-analysis showed that the pooled overall adherence rate across the studies was 48% (95% CI: 33-63%). There was significant difference in medication adherence between studies in rural areas and those in urban areas. Conclusion: The adherence rate to treatment remains relatively low, highlighting the urgent need for appropriate interventions to help improve medication adherence and prevent future health complications.