SURVEYING ON LEVEL OF PLASMA ASYMETRIC DIMETHYLARGININE IN END-STAGE RENAL DISEASE PATIENTS

Nguyễn Thị Thúy1,, Lê Việt Thắng2
1 108 Military Central Hospital
2 Military Hospital 103, Vietnam Military Medical University

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Abstract

Objectives: Surveying on plasma asymmetric dimethylarginine in end-stage renal disease patients who were indicated kidney transplantation and association with cardiovascular risk factors. Subjects and Methods: A controlled cross-sectional study in 118 end-stage renal disease (ESRD) patients who have indication kidney transplantation and 83 controlled healthy people at 103 Military hospital from March/2018 to April/2020. Results: The median concentration of plasma ADMA in the patient group: 0.61 µmol/l was higher than the control group: 0.32 µmol/l with p < 0.001. There were 75.4% of patients increased plasma ADMA. There were correlation between ADMA level and dislipidemia (OR= 6.19), overweight or obesity (OR = 4.71), smoke (OR = 3.58). Conclusion: Elevated plasma ADMA concentrations are common and associated with some cardiovascular risk factors in ESRD patients.

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References

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